31 August 2014

Acetyl-CoA Connects Many Catabolic Pathways

Acetyl CoA is the central molecule connecting the catabolism of Glucose, Fatty Acids, and Amino Acids.

This video takes a close look at the production of Pyruvate and Acetyl CoA via various catabolic pathways.
Time is spent explaining why even chain fatty acids cannot be converted into Glucose

NOTE: The exception to this rule is not explored in this video.
   The exception is that fatty acids with an odd number of carbons will be converted serially to Acetyl-CoA until a small odd number of carbons is left, at which point it can be converted into a downstream molecule in the TCA cyle and produce one new molecule of Oxaloacetate, which can be used in gluconeogenesis.
  This topic may be explored more in a video focusing on beta-oxidation of fatty acids.

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