31 August 2014

Hereditary Nonspherocytic Hemolytic Anemia

In this video, I explore the big picture look at Carbohydrate Metabolism with a special look at a Side reaction to produce 2,3-Bisphosphoglycerate

The production of 2,3-BPG is important to Red blood cells. It binds to Hemoglobin and helps it to unload O2 in peripheral tissue.
Problems with Hexokinase or Bisphosphoglycerate mutase are implicated in hereditary nonspherocytic anemia

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